- 产品信息
商品描述
靶点-Target
FA10
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
15kD,53kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FA10 (light chain, Cleaved-Arg179)
特异性
This antibody detects endogenous levels of Human FA10 (light chain, Cleaved-Arg179, protein was cleaved amino acid sequence between )
基因名称
F10
蛋白名称
FA10 (light chain, Cleaved-Arg179)
别名
Coagulation factor X;Stuart factor;Stuart-Prower factor;[Cleaved into: Factor X light chain;Factor X heavy chain;Activated factor Xa heavy chain]
Organism-1
Human
基因ID-1
2159
SwissProt-1
P00742
Organism-2
Mouse
基因ID-2
14058
SwissProt-2
O88947
Organism-3
Rat
基因ID-3
29243
SwissProt-3
Q63207
背景
catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.,function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.,online information:Factor X entry,PTM:N- and O-glycosylated.,PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,PTM:The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.,tissue specificity:Plasma; synthesized in the liver.,
细胞定位
Secreted.





