FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ENTK
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ENTK (light chain, Cleaved-Ile785)
特异性
This antibody detects endogenous levels of Human ENTK (light chain, Cleaved-Ile785, protein was cleaved amino acid sequence between 785-786 )
基因名称
TMPRSS15 ENTK PRSS7
蛋白名称
ENTK (light chain, Cleaved-Ile785)
别名
Enteropeptidase;Enterokinase;Serine protease 7;Transmembrane protease serine 15;[Cleaved into: Enteropeptidase non-catalytic heavy chain;Enteropeptidase catalytic light chain]
Organism-1
Human
基因ID-1
5651
SwissProt-1
P98073
Organism-2
Mouse
基因ID-2
19146
SwissProt-2
P97435
背景
catalytic activity:Activation of trypsinogen by selective cleavage of 6-Lys-|-Ile-7 bond.,disease:Defects in PRSS7 are a cause of enterokinase deficiency [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.,function:Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.,PTM:The chains are derived from a single precursor that is cleaved by a trypsin-like protease.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 MAM domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SEA domain.,similarity:Contains 1 SRCR domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 LDL-receptor class A domains.,subunit:Heterodimer of a catalytic (light) chain and a multidomain (heavy) chain linked by a disulfide bond.,tissue specificity:Intestinal brush border.,
细胞定位
Membrane ; Single-pass type II membrane protein .
