FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CFAD
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CFAD (Cleaved-Ile26)
特异性
This antibody detects endogenous levels of Human CFAD (Cleaved-Ile26, protein was cleaved amino acid sequence between 25-26 )
基因名称
CFD DF PFD
蛋白名称
CFAD (Cleaved-Ile26)
别名
Complement factor D;Adipsin;C3 convertase activator;Properdin factor D;
Organism-1
Human
基因ID-1
1675
SwissProt-1
P00746
Organism-2
Mouse
基因ID-2
11537
SwissProt-2
P03953
Organism-3
Rat
基因ID-3
54249
SwissProt-3
P32038
背景
catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,
细胞定位
Secreted.
