FGF-2 Polyclonal Antibody
¥680.00
FA11 (heavy chain, Cleaved-Arg387) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
一键复制产品信息
产品规格：
- 50μL
- 100μL
货号：
FAB2600123
- 产品信息
商品描述
靶点-Target
FA11
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD,66kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FA11 (heavy chain, Cleaved-Arg387)
特异性
This antibody detects endogenous levels of Human, Mouse FA11 (heavy chain, Cleaved-Arg387, protein was cleaved amino acid sequence between 387-388 )
基因名称
F11
蛋白名称
FA11 (heavy chain, Cleaved-Arg387)
别名
Coagulation factor XI;FXI;Plasma thromboplastin antecedent;PTA;[Cleaved into: Coagulation factor XIa heavy chain;Coagulation factor XIa light chain]
Organism-1
Human
基因ID-1
2160
SwissProt-1
P03951
Organism-2
Mouse
基因ID-2
109821
SwissProt-2
Q91Y47
背景
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.
