FA9 (light chain, Cleaved-Arg191) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600120
- 产品信息
商品描述
靶点-Target
Factor IX
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
16kD,45kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FA9 (light chain, Cleaved-Arg191)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat FA9 (light chain, Cleaved-Arg191, protein was cleaved amino acid sequence between 191-200 )
基因名称
F9 Factor IX
蛋白名称
FA9 (light chain, Cleaved-Arg191)
别名
Coagulation factor IX;Christmas factor;Plasma thromboplastin component;PTC;[Cleaved into: Coagulation factor IXa light chain;Coagulation factor IXa heavy chain]
Organism-1
Human
基因ID-1
2158
SwissProt-1
P00740
Organism-2
Mouse
基因ID-2
14071
SwissProt-2
P16294
Organism-3
Rat
基因ID-3
24946
SwissProt-3
P16296
背景
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015],
细胞定位
Secreted .





