FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Caspase-10
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
58kD,23kD
推荐稀释比
WB 1:500-2000;ELISA(peptide)1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Caspase 10 (p23/17, Cleaved-Val220)
特异性
This antibody detects endogenous levels of human Caspase 10 (p23/17, Cleaved-Val220)
基因名称
CASP10 MCH4
蛋白名称
Caspase10
别名
Caspase-10;CASP-10;Apoptotic protease Mch-4;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;ICE-like apoptotic protease 4;[Cleaved into: Caspase-10 subunit p23/17;Caspase-10 subunit p12]
Organism-1
Human
基因ID-1
843
SwissProt-1
Q92851
背景
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],
细胞定位
cytosol,CD95 death-inducing signaling complex,ripoptosome,
