FGF-2 Polyclonal Antibody
¥680.00
Cleaved-PARP-1 (D214) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2600094
- 产品信息
商品描述
靶点-Target
PARP
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500-2000;IF 1:50-300;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PARP. AA range:165-214
特异性
Cleaved-PARP-1 (D214) Polyclonal Antibody detects endogenous levels of fragment of activated PARP-1 protein resulting from cleavage adjacent to D214.
基因名称
PARP1
蛋白名称
Poly [ADP-ribose] polymerase 1
别名
PARP1;ADPRT;PPOL;Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1
Organism-1
Human
基因ID-1
142
SwissProt-1
P09874
Organism-2
Mouse
SwissProt-2
P11103
背景
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of DNA damage. .
