Cleaved-Integrin α7 LC (E959) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2600084

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商品描述
  • 靶点-Target

    Integrin α7 LC

  • 反应性

    Human,Monkey

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    25kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ITGA7. AA range:940-989

  • 特异性

    Cleaved-Integrin α7 LC (E959) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α7 LC protein resulting from cleavage adjacent to E959.

  • 基因名称

    ITGA7

  • 蛋白名称

    Integrin alpha-7

  • 别名

    ITGA7;Integrin alpha-7

  • Organism-1

    Human

  • 基因ID-1

    3679

  • SwissProt-1

    Q13683

  • Organism-2

    Mouse

  • SwissProt-2

    Q61738

  • 背景

    integrin subunit alpha 7(ITGA7) Homo sapiens The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009],

  • 细胞定位

    Membrane; Single-pass type I membrane protein.