- 产品信息
商品描述
靶点-Target
Ephrin-A5
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Ephrin-A5 . at AA range: 130-210
特异性
Ephrin-A5 Polyclonal Antibody detects endogenous levels of Ephrin-A5 protein.
基因名称
EFNA5
蛋白名称
Ephrin-A5
别名
EFNA5;EPLG7;LERK7;Ephrin-A5;AL-1;EPH-related receptor tyrosine kinase ligand 7;LERK-7
Organism-1
Human
基因ID-1
1946
SwissProt-1
P52803
Organism-2
Mouse
基因ID-2
13640
SwissProt-2
O08543
Organism-3
Rat
基因ID-3
116683
SwissProt-3
P97605
背景
Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divi
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor . Membrane, caveola ; Lipid-anchor, GPI-anchor . Compartmentalized in discrete caveolae-like membrane microdomains.





