Ephrin-A5 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2600072

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商品描述
  • 靶点-Target

    Ephrin-A5

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    26kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from Ephrin-A5 . at AA range: 130-210

  • 特异性

    Ephrin-A5 Polyclonal Antibody detects endogenous levels of Ephrin-A5 protein.

  • 基因名称

    EFNA5

  • 蛋白名称

    Ephrin-A5

  • 别名

    EFNA5;EPLG7;LERK7;Ephrin-A5;AL-1;EPH-related receptor tyrosine kinase ligand 7;LERK-7

  • Organism-1

    Human

  • 基因ID-1

    1946

  • SwissProt-1

    P52803

  • Organism-2

    Mouse

  • 基因ID-2

    13640

  • SwissProt-2

    O08543

  • Organism-3

    Rat

  • 基因ID-3

    116683

  • SwissProt-3

    P97605

  • 背景

    Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divi

  • 细胞定位

    Cell membrane ; Lipid-anchor, GPI-anchor . Membrane, caveola ; Lipid-anchor, GPI-anchor . Compartmentalized in discrete caveolae-like membrane microdomains.