Cleaved-SUMO-2/3 (G93) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2600068

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商品描述
  • 靶点-Target

    SUMO-2/3

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA,CoIP

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    11kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;IP 1:50-100;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human SUMO2/3. AA range:44-93

  • 特异性

    Cleaved-SUMO-2/3 (G93) Polyclonal Antibody detects endogenous levels of fragment of activated SUMO-2/3 protein resulting from cleavage adjacent to G93.

  • 基因名称

    SUMO2 SUMO3

  • 蛋白名称

    Small ubiquitin-related modifier 2

  • 别名

    SUMO2;SMT3A;SMT3H2;Small ubiquitin-related modifier 2;SUMO-2;HSMT3;SMT3 homolog 2;SUMO-3;Sentrin-2;Ubiquitin-like protein SMT3A;Smt3A

  • Organism-1

    Human

  • 基因ID-1

    6613

  • SwissProt-1

    P61956;P55854

  • Organism-2

    Mouse

  • 基因ID-2

    170930

  • SwissProt-2

    P61957

  • Organism-3

    Rat

  • 基因ID-3

    690244

  • SwissProt-3

    P61959

  • 背景

    This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus. Nucleus, PML body.