- 产品信息
商品描述
靶点-Target
SUMO-2/3
反应性
Human,Mouse,Rat
应用
WB,ELISA,CoIP
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
11kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;IP 1:50-100;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SUMO2/3. AA range:44-93
特异性
Cleaved-SUMO-2/3 (G93) Polyclonal Antibody detects endogenous levels of fragment of activated SUMO-2/3 protein resulting from cleavage adjacent to G93.
基因名称
SUMO2 SUMO3
蛋白名称
Small ubiquitin-related modifier 2
别名
SUMO2;SMT3A;SMT3H2;Small ubiquitin-related modifier 2;SUMO-2;HSMT3;SMT3 homolog 2;SUMO-3;Sentrin-2;Ubiquitin-like protein SMT3A;Smt3A
Organism-1
Human
基因ID-1
6613
SwissProt-1
P61956;P55854
Organism-2
Mouse
基因ID-2
170930
SwissProt-2
P61957
Organism-3
Rat
基因ID-3
690244
SwissProt-3
P61959
背景
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Nucleus, PML body.





