FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MMP-3
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MMP3. AA range:81-130
特异性
Cleaved-MMP-3 (F100) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-3 protein resulting from cleavage adjacent to F100.
基因名称
MMP3
蛋白名称
Stromelysin-1
别名
MMP3;STMY1;Stromelysin-1;SL-1;Matrix metalloproteinase-3;MMP-3;Transin-1
Organism-1
Human
基因ID-1
4314
SwissProt-1
P08254
Organism-2
Mouse
SwissProt-2
P28862
背景
matrix metallopeptidase 3(MMP3) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix .
