FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MMP-15
反应性
Human,Monkey
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
61kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MMP15. AA range:113-162
特异性
Cleaved-MMP-15 (Y132) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-15 protein resulting from cleavage adjacent to Y132.
基因名称
MMP15
蛋白名称
Matrix metalloproteinase-15
别名
MMP15;Matrix metalloproteinase-15;MMP-15;Membrane-type matrix metalloproteinase 2;MT-MMP 2;MTMMP2;Membrane-type-2 matrix metalloproteinase;MT2-MMP;MT2MMP;SMCP-2
Organism-1
Human
基因ID-1
4324
SwissProt-1
P51511
Organism-2
Mouse
SwissProt-2
O54732
背景
This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016],
细胞定位
Membrane ; Single-pass type I membrane protein ; Extracellular side .
