Caspase-14 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600019
- 产品信息
商品描述
靶点-Target
Caspase-14
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Caspase-14 . at AA range: 110-190
特异性
Caspase-14 Polyclonal Antibody detects endogenous levels of Caspase-14 protein.
基因名称
CASP14
蛋白名称
Caspase14
别名
CASP14;Caspase-14;CASP-14
Organism-1
Human
基因ID-1
23581
SwissProt-1
P31944
Organism-2
Mouse
SwissProt-2
O89094
背景
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus .





