Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2600008
- 产品信息
商品描述
靶点-Target
Caspase-6
反应性
Human,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
20kD,35kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179
特异性
Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D179.
基因名称
CASP6
蛋白名称
Caspase6
别名
CASP6;MCH2;Caspase-6;CASP-6;Apoptotic protease Mch-2
Organism-1
Human
基因ID-1
839
SwissProt-1
P55212
Organism-2
Mouse
SwissProt-2
O08738
Organism-3
Rat
SwissProt-3
O35397
背景
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015],
细胞定位
Cytoplasm . Nucleus .





