FGF-2 Polyclonal Antibody
¥680.00
Caspase-3 mouse Monoclonal Antibody(5H10)
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2600001
- 产品信息
商品描述
反应性
Human,Rat,Mouse
应用
WB,IHC-p,IF(paraffin section)
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
17、32
推荐稀释比
WB: 500-2000;IHC 1:100-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-20°C/1 year
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
5H10
免疫原
Synthetic Peptide of Caspase-3 at AA range of 20-100
特异性
Caspase-3 protein detects endogenous levels of CASP3
基因名称
CASP3
蛋白名称
Caspase3
别名
CASP3
Organism-1
Human
基因ID-1
836
SwissProt-1
P42574
Organism-2
Mouse
SwissProt-2
P70677
Organism-3
Rat
SwissProt-3
P55213
背景
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm.
