FGF-2 Polyclonal Antibody
¥680.00
商品描述
靶点-Target
PDX1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
31kD
MW(Observed)
42kD
推荐稀释比
IHC 1:100-1:500;WB 1:500-1:20000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT1159R
特异性
Endogenous
基因名称
PDX1
蛋白名称
Pancreas/duodenum homeobox protein 1
别名
PDX1;IPF1;Pancreas/duodenum homeobox protein 1;PDX-1;Glucose-sensitive factor;GSF;Insulin promoter factor 1;IPF-1;Insulin upstream factor 1;IUF-1;Islet/duodenum homeobox-1;IDX-1;Somatostatin-transactivating factor 1;STF-1
Organism-1
Human
基因ID-1
3651
SwissProt-1
P52945
Organism-2
Mouse
基因ID-2
18609
SwissProt-2
P52946
Organism-3
Rat
基因ID-3
29535
SwissProt-3
P52947
背景
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Cytoplasm, cytosol .
