FGF-2 Polyclonal Antibody
¥680.00
商品描述
靶点-Target
SIRT3
反应性
Human,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SIRT3. AA range:350-399
特异性
SIRT3 Polyclonal Antibody detects endogenous levels of SIRT3 protein.
基因名称
SIRT3
蛋白名称
NAD-dependent protein deacetylase sirtuin-3 mitochondrial
别名
SIRT3;SIR2L3;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;hSIRT3;Regulatory protein SIR2 homolog 3;SIR2-like protein 3
Organism-1
Human
基因ID-1
23410
SwissProt-1
Q9NTG7
Organism-2
Mouse
SwissProt-2
Q8R104
背景
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix .
