商品描述
靶点-Target
HDAC1
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
55kD
MW(Observed)
62kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR1326
免疫原
Synthesized peptide derived from human protein. AA range: 300-482
特异性
This antibody detects endogenous levels of HDAC1 protein.
基因名称
HDAC1 RPD3L1
蛋白名称
Histone deacetylase 1 (HD1) (EC 3.5.1.98)
别名
Histone deacetylase 1;HD1;
Organism-1
Human
基因ID-1
3065
SwissProt-1
Q13547
Organism-2
Mouse
基因ID-2
433759
SwissProt-2
O09106
背景
histone deacetylase 1(HDAC1) Homo sapiens Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008],





