FGF-2 Polyclonal Antibody
¥680.00
商品描述
靶点-Target
Dkk-1
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
29kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of Dkk-1 expressed in E. Coli.
特异性
Dkk-1 Monoclonal Antibody detects endogenous levels of Dkk-1 protein.
基因名称
DKK1
蛋白名称
Dickkopf-related protein 1
别名
DKK1;Dickkopf-related protein 1;Dickkopf-1;Dkk-1;hDkk-1;SK
Organism-1
Human
基因ID-1
22943
SwissProt-1
O94907
Organism-2
Mouse
SwissProt-2
O54908
背景
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.
