DDR2 Monoclonal Antibody

活动价：

¥880.00

市场价：¥1280.00

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产品规格：

货号：

FAB2600580

WB IHC IF ELISA

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推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)

特异性
DDR2 Monoclonal Antibody detects endogenous levels of DDR2 protein.
基因名称
DDR2
蛋白名称
Discoidin domain-containing receptor 2
别名
DDR2;NTRKR3;TKT;TYRO10;Discoidin domain-containing receptor 2;Discoidin domain receptor 2;CD167 antigen-like family member B;Discoidin domain-containing receptor tyrosine kinase 2;Neurotrophic tyrosine kinase;receptor-related 3;Re

背景
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcr
细胞定位
Cell membrane ; Single-pass type I membrane protein .